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Lupkynis (voclosporin capsules – Aurinia)Cigna

Lupus nephritis

Initial criteria

  • Patient is age ≥ 18 years; AND
  • Diagnosis of lupus nephritis has been confirmed on biopsy (e.g., WHO class III, IV, or V lupus nephritis); AND
  • The medication is being used concurrently with an immunosuppressive regimen (e.g., mycophenolate mofetil or azathioprine with a systemic corticosteroid); AND
  • Patient has an estimated glomerular filtration rate (eGFR) > 45 mL/min/m2; AND
  • The medication is prescribed by or in consultation with a nephrologist or rheumatologist.

Reauthorization criteria

  • Patient is age ≥ 18 years; AND
  • The medication is being used concurrently with an immunosuppressive regimen (e.g., mycophenolate mofetil or azathioprine with a systemic corticosteroid); AND
  • Patient has responded to Lupkynis as determined by the prescriber (e.g., improvement in organ dysfunction, reduction in flares, reduction in corticosteroid dose, decrease of anti-double stranded DNA titer, and improvement in complement levels [C3, C4]); AND
  • The medication is prescribed by or in consultation with a nephrologist or rheumatologist.

Approval duration

initial 6 months; reauth 1 year