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Marinol (dronabinol capsules)Cigna

Nausea and vomiting associated with cancer chemotherapy

Preferred products

  • generic dronabinol capsules

Initial criteria

  • Approve for 1 year if BOTH of the following are met:
  • A) Patient has failed to respond adequately to at least TWO conventional antiemetic treatments;
  • Examples of conventional antiemetic treatments include selective serotonin [5-HT3] receptor antagonists (ondansetron, granisetron, Anzemet [dolasetron], Aloxi [palonosetron injection]), Akynzeo (netupitant/palonosetron capsules), Emend (aprepitant capsules), Varubi (rolapitant tablets), metoclopramide, prochlorperazine, dexamethasone, olanzapine.
  • B) For Marinol (dronabinol capsules): Patient meets ONE of the following:
  • i. Generic dronabinol capsules are requested; OR
  • ii. If brand Marinol is being requested, the patient meets BOTH of the following:
  • a) Patient has tried generic dronabinol capsules; AND
  • b) The Brand product is being requested due to a formulation difference in the inactive ingredient(s) [e.g., difference in dyes, fillers, preservatives] between the Brand and the bioequivalent generic product which, per the prescriber, would result in a significant allergy or serious adverse reaction.
  • For Syndros (dronabinol oral solution): Patient meets ONE of the following:
  • i. Patient has tried generic dronabinol capsules; OR
  • ii. Patient cannot swallow or has difficulty swallowing capsules.

Approval duration

1 year