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NucalaCigna

Eosinophilic Granulomatosis with Polyangiitis (EGPA)

Initial criteria

  • Age ≥ 18 years
  • Has active, non-severe EGPA (vasculitis without life- or organ-threatening manifestations)
  • Currently receiving a systemic corticosteroid and has been on therapy for a minimum of 4 weeks
  • Has ONE of the following: blood eosinophil level ≥ 150 cells/µL within the previous 4 weeks OR blood eosinophil level ≥ 150 cells/µL prior to treatment with any monoclonal antibody therapy that may alter blood eosinophil levels
  • Prescribed by or in consultation with an allergist, immunologist, pulmonologist, or rheumatologist

Reauthorization criteria

  • Has already received at least 9 months of therapy with Nucala
  • Responded to therapy as determined by the prescriber (e.g., reduced rate of relapse, corticosteroid dose reduction, reduced eosinophil levels)

Approval duration

initial 9 months, reauth 1 year