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Signifor (pasireotide subcutaneous injection - Novartis)Cigna

Cushing’s disease

Initial criteria

  • Patient is age ≥ 18 years; AND
  • According to the prescriber, the patient is not a candidate for surgery OR surgery has not been curative; AND
  • The medication is prescribed by or in consultation with an endocrinologist or a physician who specializes in the treatment of Cushing’s syndrome

Reauthorization criteria

  • Patient has had a response, as determined by the prescriber; AND
  • Patient is continuing therapy to maintain response

Approval duration

initial 4 months; reauth 1 year