Skip to content
The Policy VaultThe Policy Vault

Tagrisso (osimertinib tablets – AstraZeneca)Cigna

Non-Small Cell Lung Cancer – Advanced or Metastatic Disease

Initial criteria

  • Patient age ≥ 18 years
  • Patient meets ONE of the following (i or ii):
  • i. Patient has epidermal growth factor receptor (EGFR) mutation-positive disease as detected by an approved test
  • Note: Examples of EGFR mutation-positive non-small cell lung cancer include the following: exon 19 deletion, exon 21 (L858R) substitution mutations, L861Q, G719X, and S768I
  • ii. Patient meets BOTH of the following (a and b):
  • a) Patient has epidermal growth factor receptor (EGFR) T790M mutation-positive disease as detected by an approved test
  • b) Patient has progressed on treatment with at least one of the EGFR tyrosine kinase inhibitors (erlotinib, Iressa, Vizimpro, Gilotrif)

Approval duration

1 year