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Truqap (capivasertib tablets – AstraZeneca)Cigna

Breast Cancer

Initial criteria

  • Patient age ≥ 18 years
  • Patient has locally advanced or metastatic disease
  • Patient has hormone receptor-positive (HR+) disease
  • Patient has human epidermal growth factor receptor 2 (HER2)-negative disease
  • Patient has at least one phosphatidylinositol 3-kinase (PIK3CA), serine/threonine protein kinase (AKT1), or phosphatase and tensin homolog (PTEN)-alteration
  • Patient meets ONE of the following (i or ii):
  • i. Patient has had progression with at least one endocrine-based regimen in the metastatic setting AND progression with at least one cyclin-dependent kinase (CDK) 4/6 inhibitor in the metastatic setting
  • ii. Patient has recurrence on or within 12 months of completing adjuvant endocrine therapy

Approval duration

1 year