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Zelboraf (vemurafenib tablets)Cigna

Central Nervous System Cancer

Initial criteria

  • Medication is being used for ONE of the following: adjuvant treatment of pilocytic astrocytoma, pleomorphic xanthoastrocytoma, circumscribed ganglioglioma/neuroglioma/glioneuronal tumor, or pediatric diffuse high-grade glioma; OR recurrent or progressive disease for high-grade glioma, circumscribed glioma, or glioblastoma; OR brain metastases due to melanoma
  • Patient has BRAF V600 mutation-positive disease
  • Medication is prescribed in combination with Cotellic (cobimetinib tablets)

Approval duration

1 year