Afinitor Disperz (everolimus tablets for oral suspension) — Highmark
TSC with subependymal giant cell astrocytoma (SEGA) that cannot be curatively resected
Preferred products
- generic everolimus tablets
 - generic everolimus tablets for suspension
 
Initial criteria
- For TSC with SEGA: age ≥ 1 year AND diagnosis of TSC with SEGA AND not a candidate for curative surgical resection AND (failed or intolerant to plan-preferred generic everolimus tablets OR unable to swallow generic everolimus tablets) AND if brand Afinitor Disperz requested, failed or intolerant to generic everolimus tablets for suspension
 - For TSC-associated partial-onset seizures: age ≥ 2 years AND using Afinitor Disperz as adjunctive treatment for TSC-associated partial-onset seizures AND if brand Afinitor Disperz requested, failed or intolerant to generic everolimus tablets for suspension
 
Reauthorization criteria
- Prescriber attests member is tolerating therapy AND has shown a therapeutic response defined as disease improvement or delayed disease progression
 - If brand Afinitor Disperz requested, documentation that AB-rated generic is ineffective or not tolerated
 
Approval duration
24 months