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Epidiolex (cannabidiol oral solution)Highmark

Lennox-Gastaut syndrome (LGS)

Preferred products

  • valproic acid
  • divalproex sodium
  • topiramate
  • lamotrigine
  • clobazam

Initial criteria

  • age ≥ 1 year
  • diagnosis of Lennox-Gastaut syndrome (ICD-10: G40.81)
  • treatment is in combination with other conventional agents
  • therapeutic failure, contraindication, or intolerance to at least two of the following plan-preferred generic products: valproic acid or divalproex sodium, topiramate, lamotrigine, clobazam

Reauthorization criteria

  • prescriber attests that the member has experienced a reduction in seizure frequency from baseline

Approval duration

12 months