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HumatropeHighmark

Short Stature Homeobox-containing gene (SHOX) Deficiency

Initial criteria

  • Diagnosis of SHOX deficiency
  • If female, bone age ≤ 14 years OR if male, bone age ≤ 16 years
  • If request is for a non-preferred growth hormone product, member has experienced therapeutic failure or intolerance to all plan-preferred products

Reauthorization criteria

  • Clinical documentation indicating a growth velocity of at least 2 cm/year
  • Female with chronological age > 14 years and bone age ≤ 14 years OR male with chronological age > 16 years and bone age ≤ 16 years OR female with chronological age ≤ 14 years OR male with chronological age ≤ 16 years

Approval duration

12 months