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Idhifa (enasidenib)Highmark

Relapsed or refractory acute myeloid leukemia (AML) with an isocitrate dehydrogenase-2 (IDH2) mutation

Initial criteria

  • age ≥ 18 years
  • Diagnosis of relapsed or refractory acute myeloid leukemia (AML, ICD-10: C92.5)
  • Member is isocitrate dehydrogenase-2 (IDH2) mutation-positive as detected by an FDA-approved test

Reauthorization criteria

  • Prescriber attests that the member is tolerating therapy
  • Member has experienced a therapeutic response defined as one (1) of the following:
  • Disease improvement OR delayed disease progression

Approval duration

12 months