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Kisqali Femara Co-Pack (ribociclib; letrozole)Highmark

HR-positive, HER2-negative advanced or metastatic breast cancer (initial endocrine-based therapy)

Initial criteria

  • age ≥ 18 years
  • for early breast cancer: diagnosis of HR-positive, HER2-negative stage II or III disease at high risk of recurrence, used as adjuvant therapy
  • for advanced or metastatic disease: diagnosis of HR-positive, HER2-negative advanced or metastatic breast cancer (ICD-10: C50), used as initial endocrine-based therapy

Reauthorization criteria

  • member is tolerating therapy AND has experienced a therapeutic response defined as disease improvement OR delayed disease progression

Approval duration

12 months