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Modeyso (dordaviprone)Highmark

diffuse midline glioma harboring an H3 K27M mutation with progressive disease following prior therapy

Initial criteria

  • age ≥ 1 year
  • diagnosis of diffuse midline glioma
  • disease harbors an H3 K27M mutation
  • progressive disease following prior therapy

Reauthorization criteria

  • prescriber attests that the member is tolerating therapy
  • therapeutic response defined as one of the following: 1) disease improvement OR 2) delayed disease progression

Approval duration

12 months