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Palforzia [peanut (Arachis hypogaea) allergen powder-dnfp]Highmark

Mitigation of allergic reactions, including anaphylaxis, that may occur with accidental exposure to peanut in patients with a confirmed diagnosis of peanut allergy

Initial criteria

  • Prescribed by or in consultation with an allergist or immunologist
  • Member meets one of the following: age between 1 and 17 years for initial dose escalation OR age ≥ 1 year for up-dosing and maintenance
  • Confirmed diagnosis of peanut allergy (ICD10: Z91.010) demonstrated by one of the following: peanut-specific skin prick test (SPT) OR peanut-specific IgE (sIgE) antibodies
  • Member experienced an allergic reaction to peanut
  • Member will be on a peanut-avoidant diet while on Palforzia therapy
  • Member does not have uncontrolled asthma
  • Member does not have eosinophilic esophagitis or eosinophilic gastrointestinal disease
  • Member has a documented prescription for epinephrine

Reauthorization criteria

  • Member has experienced a positive clinical response to therapy
  • Member requires continuation of therapy
  • Member has not missed three or more consecutive days of therapy as evidenced by claims
  • Member will continue a peanut-avoidant diet while on Palforzia therapy

Approval duration

12 months