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Qulipta (atogepant)Highmark

migraine (episodic or chronic)

Initial criteria

  • age ≥ 18 years
  • diagnosis of migraine (ICD-10: G43) classified as either episodic migraine (4–14 headache days per month) OR chronic migraine (≥15 headache days per month of which ≥8 are migraine days)
  • prescriber attests to: (a) baseline average monthly migraine days, (b) headaches not due to medication rebound/overutilization or lifestyle factors, AND (c) therapeutic failure or intolerance to one (1) agent from two (2) different prophylactic migraine medication classes OR all are contraindicated (alpha-agonists; ACE inhibitors or ARBs; anti-epileptics; beta-blockers; calcium channel blockers; SNRIs; tricyclic antidepressants)
  • if two chemically distinct CGRP inhibitors will be used concurrently for prevention and acute use, prescriber attests that benefits outweigh the risks

Reauthorization criteria

  • reduction in migraine days per month by at least 50% from baseline OR episodic migraine: ≥4-day reduction from baseline OR chronic migraine: ≥5-day reduction from baseline
  • subsequent reauthorizations require sustained improvement