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Relistor (methylnaltrexone bromide) tabletsHighmark

OIC due to chronic pain related to prior cancer or its treatment not requiring frequent opioid dosage escalation

Preferred products

  • Movantik
  • generic lubiprostone
  • Symproic

Initial criteria

  • age ≥ 18 years
  • diagnosis of OIC (ICD-10: K59.03) due to chronic non-cancer pain OR OIC (ICD-10: K59.03) due to chronic pain related to prior cancer or its treatment and does not require frequent opioid dosage escalation
  • taking opioid medications for at least one month
  • therapeutic failure, contraindication, or intolerance to scheduled dosing of one laxative
  • therapeutic failure, contraindication, or intolerance to all of the following plan-preferred products: Movantik, generic lubiprostone, Symproic

Reauthorization criteria

  • provider attests that the member has experienced positive clinical response to therapy

Approval duration

12 months