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Retevmo (selpercatinib)Highmark

locally advanced or metastatic RET fusion-positive solid tumors

Initial criteria

  • age ≥ 2 years
  • diagnosis of locally advanced or metastatic solid tumors
  • disease harbors a RET gene fusion as detected by an FDA approved test
  • no satisfactory alternative treatments OR tumor(s) have progressed on or following prior systemic treatment

Reauthorization criteria

  • prescriber attests that member is tolerating therapy AND has experienced a therapeutic response defined as disease improvement OR delayed disease progression

Approval duration

12 months