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Somavert (pegvisomant)Highmark

acromegaly

Preferred products

  • generic octreotide acetate

Initial criteria

  • age ≥ 18 years
  • diagnosis of acromegaly (ICD-10: E22.0)
  • high pretreatment insulin-like growth factor-1 (IGF-1) based on laboratory reference range
  • member has had either inadequate or partial response to surgery or radiotherapy OR is not a candidate for surgery or radiotherapy
  • therapeutic failure, contraindication, or intolerance to generic octreotide acetate

Reauthorization criteria

  • Decreased IGF-1 from baseline OR Normalized IGF-1 from baseline

Approval duration

12 months