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Sunosi (solriamfetol)Highmark

narcolepsy

Preferred products

  • generic modafinil
  • generic CNS stimulant (e.g., dextroamphetamine, methylphenidate)

Initial criteria

  • age ≥ 18 years
  • diagnosis of narcolepsy (ICD-10: G47.41)
  • meets one of the following: (a) MSLT substantiating mean sleep latency ≤ 8 minutes AND ≥ 2 SOREMPs OR (b) polysomnography and MSLT substantiating mean sleep latency ≤ 8 minutes AND ≥1 SOREMP on each test OR (c) documented hypocretin-1 deficiency defined as cerebrospinal fluid hypocretin-1 <110 pg/mL or < one-third of normal value
  • prescriber provides documentation of baseline ESS or MWT for excessive daytime sleepiness
  • meets one of the following: (a) if narcolepsy with cataplexy, has therapeutic failure, contraindication, or intolerance to a generic CNS stimulant (e.g., dextroamphetamine) OR (b) if narcolepsy without cataplexy, has therapeutic failure, contraindication, or intolerance to all of the following: generic modafinil AND a generic CNS stimulant (e.g., dextroamphetamine, methylphenidate)

Reauthorization criteria

  • prescriber attests member experienced a decrease in daytime sleepiness with improvement on ESS or MWT compared to baseline

Approval duration

12 months