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Tazverik (tazemetostat)Highmark

Relapsed or refractory follicular lymphoma (FL) (EZH2 mutation positive after ≥2 prior systemic therapies OR no satisfactory alternative treatment options)

Initial criteria

  • age ≥ 18 years
  • diagnosis of relapsed or refractory follicular lymphoma (ICD-10: C82)
  • EITHER tumors positive for an EZH2 mutation as detected by an FDA-approved test AND member has received at least two prior systemic therapies OR prescriber attests member has no satisfactory alternative treatment options

Reauthorization criteria

  • prescriber attests member is tolerating therapy
  • prescriber attests member has experienced a therapeutic response defined as disease improvement OR delayed disease progression

Approval duration

12 months