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Tibsovo (ivosidenib)Highmark

relapsed or refractory myelodysplastic syndromes (MDS)

Initial criteria

  • age ≥ 18 years
  • diagnosis of relapsed or refractory MDS (ICD-10 D46)
  • disease is IDH1 mutation-positive as detected by an FDA-approved companion diagnostic test

Reauthorization criteria

  • prescriber attests that the member is tolerating therapy and has experienced a therapeutic response defined as either disease improvement or delayed disease progression

Approval duration

12 months