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Truqap (capivasertib)Highmark

locally advanced or metastatic breast cancer

Initial criteria

  • age ≥ 18 years
  • diagnosis of locally advanced or metastatic breast cancer (ICD-10: C50)
  • Truqap is used in combination with fulvestrant
  • tumor status is HR-positive, HER2-negative
  • presence of one of the following alterations detected by an FDA-approved test: PIK3CA OR AKT1 OR PTEN
  • disease has progressed on at least one endocrine-based regimen in the metastatic setting OR recurrence occurred on or within 12 months of completing adjuvant therapy

Reauthorization criteria

  • prescriber attests that member is tolerating therapy
  • therapeutic response is observed as disease improvement OR delayed disease progression

Approval duration

12 months