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Vijoice (alpelisib)Highmark

PIK3CA-related overgrowth spectrum (PROS) with severe manifestations

Preferred products

  • Piqray 250 mg (alpelisib)

Initial criteria

  • age ≥ 2 years
  • Diagnosis of PIK3CA-related overgrowth spectrum (PROS) with severe manifestations
  • If request is for Vijoice 250 mg, member has experienced therapeutic failure or intolerance to Piqray 250 mg

Reauthorization criteria

  • Prescriber attests the member is tolerating therapy AND has experienced a therapeutic response defined as disease improvement OR delayed disease progression

Approval duration

12 months