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VoseviHighmark

Chronic hepatitis C virus (HCV) infection – treatment-experienced adults

Preferred products

  • Vosevi
  • Mavyret
  • Epclusa
  • Harvoni

Initial criteria

  • age ≥ 18 years
  • diagnosis of chronic HCV (ICD-10: B18.2)
  • prescriber documents previous HCV therapies with reason for discontinuation or failure
  • prescriber documents cirrhosis status and liver transplant history
  • prescribed regimen is appropriate per FDA labeling and/or AASLD/IDSA guidelines (see table 2)
  • prescriber attests member or guardian educated on potential adverse effects of alcohol or IV drug abuse including risk of misuse, abuse, and addiction
  • if member has alcohol use disorder OR IV drug abuse OR history of substance abuse within past 6 months, prescriber attests that an offer of referral for substance abuse treatment and care management was made
  • appropriate resistance-associated substitutions (RASs) testing performed as applicable
  • if request is for non-preferred product, member has contraindication to or is not a candidate for all preferred regimens