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Xadago (safinamide)Highmark

Parkinson’s disease experiencing 'off' episodes

Preferred products

  • generic rasagiline
  • selegiline
  • pramipexole
  • ropinirole
  • entacapone

Initial criteria

  • age ≥ 18 years
  • diagnosis of Parkinson’s disease (ICD-10: G20)
  • Xadago will be used as an adjunct to levodopa/carbidopa
  • member is experiencing wearing off (e.g., 'off' episodes) despite optimized levodopa/carbidopa therapy
  • member has experienced therapeutic failure, contraindication, or intolerance to generic rasagiline
  • member has experienced therapeutic failure, contraindication, or intolerance to two of the following: selegiline, pramipexole, ropinirole, entacapone

Reauthorization criteria

  • prescriber attests that the member has experienced positive clinical response to therapy

Approval duration

12 months