Xadago (safinamide) — Highmark
Parkinson’s disease experiencing 'off' episodes
Preferred products
- generic rasagiline
 - selegiline
 - pramipexole
 - ropinirole
 - entacapone
 
Initial criteria
- age ≥ 18 years
 - diagnosis of Parkinson’s disease (ICD-10: G20)
 - Xadago will be used as an adjunct to levodopa/carbidopa
 - member is experiencing wearing off (e.g., 'off' episodes) despite optimized levodopa/carbidopa therapy
 - member has experienced therapeutic failure, contraindication, or intolerance to generic rasagiline
 - member has experienced therapeutic failure, contraindication, or intolerance to two of the following: selegiline, pramipexole, ropinirole, entacapone
 
Reauthorization criteria
- prescriber attests that the member has experienced positive clinical response to therapy
 
Approval duration
12 months