Skip to content
The Policy VaultThe Policy Vault

XolairHighmark

chronic rhinosinusitis with nasal polyps (CRSwNP)

Initial criteria

  • age ≥ 18 years
  • diagnosis of nasal polyps (ICD-10 J33.0, J33.1, J33.8, J33.9) with chronic rhinosinusitis
  • Xolair will be add-on to nasal corticosteroid maintenance treatment
  • prescriber attests member is appropriate candidate for self-administration, meeting ALL: (a) no history of anaphylaxis AND (b) will receive at least 3 doses of Xolair (syringe or vial) under healthcare provider guidance with no hypersensitivity reactions
  • prescriber submits documentation of current weight AND pretreatment serum IgE

Reauthorization criteria

  • prescriber submits documentation of current weight AND pretreatment serum IgE
  • prescriber attests one of the following: (a) decrease in nasal polyp score OR (b) reduction in nasal congestion/obstruction severity score
  • member continues using Xolair with nasal corticosteroid as add-on maintenance therapy