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The Policy VaultThe Policy Vault

Xphozah (tenapanor)Highmark

To reduce serum phosphorus in adults with chronic kidney disease (CKD) on dialysis as add-on therapy in patients who have an inadequate response to phosphate binders or who are intolerant of any dose of phosphate binder therapy

Preferred products

  • Calcium acetate
  • Sevelamer carbonate tablet

Initial criteria

  • age ≥ 18 years
  • Diagnosis of CKD and on dialysis (ICD-10: Z99.2)
  • AND member meets one of the following:
  • 1. Using Xphozah as add-on therapy and has had inadequate response to all of the following plan-preferred phosphate binders:
  • - Calcium acetate
  • - Sevelamer carbonate tablet
  • OR
  • 2. Experienced intolerance or contraindication to all of the following plan-preferred phosphate binders:
  • - Calcium acetate
  • - Sevelamer carbonate tablet

Reauthorization criteria

  • Prescriber attests that the member has experienced positive clinical response to therapy

Approval duration

12 months