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adalimumab productsMedica

juvenile idiopathic arthritis (juvenile rheumatoid arthritis, juvenile spondyloarthropathy/active sacroiliac arthritis)

Initial criteria

  • age ≥ 2 years
  • EITHER (a) trial of one systemic therapy (e.g., methotrexate, sulfasalazine, leflunomide, or NSAID) OR (b) starting concurrently with methotrexate/sulfasalazine/leflunomide OR (c) absolute contraindication to these agents OR (d) aggressive disease as determined by prescriber
  • prescribed by or in consultation with a rheumatologist

Reauthorization criteria

  • patient established on therapy ≥ 6 months
  • beneficial clinical response by objective measure (e.g., MD global, PGA, JDAS, JSpADA, serum markers, or reduced corticosteroid dosage) OR improvement in symptoms/function/morning stiffness vs baseline

Approval duration

initial 6 months, reauth 1 year