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amifampridineMedica

Lambert-Eaton myasthenic syndrome (LEMS)

Initial criteria

  • age ≥ 6 years
  • according to the prescriber, patient has confirmed LEMS based on at least ONE of the following: electrodiagnostic study (e.g., repetitive nerve stimulation) OR anti-P/Q-type voltage-gated calcium channels antibody testing
  • patient does not have a history of seizures
  • the medication is being prescribed by or in consultation with a neurologist or a neuromuscular specialist

Reauthorization criteria

  • according to the prescriber, the patient is continuing to derive benefit from amifampridine (e.g., improved muscle strength and improvements in mobility)

Approval duration

initial: 3 months; reauthorization: 1 year