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Ayvakit (avapritinib)Medica

Gastrointestinal stromal tumor (GIST)

Preferred products

  • imatinib
  • sunitinib
  • Sprycel (dasatinib)
  • Stivarga (regorafenib)
  • Qinlock (ripretinib)

Initial criteria

  • Patient is age ≥ 18 years
  • EITHER the tumor is positive for platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation (including PDGFRA D842V) OR patient has tried ALL of the following: imatinib, ONE of sunitinib or Sprycel (dasatinib), Stivarga (regorafenib), and Qinlock (ripretinib)

Approval duration

1 year