Cotellic (cobimetinib) — Medica
Central nervous system cancer with BRAF V600 mutation
Initial criteria
- Patient is age ≥ 18 years
 - Medication is being used for ONE of the following: adjuvant treatment of pilocytic astrocytoma OR pleomorphic xanthoastrocytoma OR circumscribed ganglioglioma/neuroglioma/glioneuronal tumor OR recurrent/progressive high-grade glioma OR recurrent/progressive circumscribed glioma OR recurrent/progressive glioblastoma OR brain metastases due to melanoma
 - Patient has BRAF V600 mutation-positive disease
 - Medication is prescribed in combination with Zelboraf (vemurafenib tablets)
 
Approval duration
1 year