Northera — Medica

Initial criteria

• age > 18 years
• diagnosis of symptomatic neurogenic orthostatic hypotension due to primary autonomic failure (Parkinson’s disease, multiple system atrophy, and pure autonomic failure), dopamine beta-hydroxylase deficiency, or non-diabetic autonomic neuropathy
• patient has tried two other medications for the treatment of neurogenic orthostatic hypotension (e.g., atomoxetine, dihydroergotamine, fludrocortisone, indomethacin, midodrine, pyridostigmine)
• patient has initiated non-pharmacological measures including but not limited to elevation of the head of the bed, orthostatic compression garments, and appropriate physical training
• prescribed by or in consultation with a cardiologist or neurologist

Approval duration

1 year