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Ofev (nintedanib)Medica

Chronic fibrosing interstitial lung diseases with a progressive phenotype (not associated with idiopathic pulmonary fibrosis)

Initial criteria

  • age ≥ 18 years
  • forced vital capacity (FVC) ≥ 40% of the predicted value
  • fibrosing lung disease impacting more than 10% of lung volume on high-resolution computed tomography as assessed by the prescriber
  • clinical signs of progression as assessed by the prescriber (e.g., FVC decline ≥ 10% of predicted value OR FVC decline ≥ 5% to < 10% with worsening symptoms and/or worsening imaging)
  • prescribed by or in consultation with a pulmonologist

Reauthorization criteria

  • age ≥ 18 years
  • patient is currently receiving Ofev and has experienced a beneficial response as determined by the prescriber (e.g., stabilization or improvement in pulmonary function or symptoms)
  • prescribed by or in consultation with a pulmonologist

Approval duration

1 year