Stivarga (regorafenib) — Medica
Colon cancer
Initial criteria
- age ≥ 18 years
- advanced or metastatic disease
- previously treated with a fluoropyrimidine (e.g., capecitabine, 5-fluorouracil [5-FU])
- previously treated with oxaliplatin
- previously treated with irinotecan
- EITHER (tumor/metastases are RAS wild-type AND patient has tried Erbitux (cetuximab) OR Vectibix (panitumumab) OR tumor did not originate on left side of colon) OR tumor/metastases have RAS mutation (KRAS or NRAS)
Approval duration
1 year