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Tevimbra (tislelizumab-jsgr)Medica

Esophageal and Esophagogastric Junction Cancers

Initial criteria

  • age ≥ 18 years
  • unresectable locally advanced, recurrent, or metastatic disease
  • ONE of the following: (i) esophageal squamous cell carcinoma AND ALL of: PD-L1 combined positive score ≥ 1 by approved test, used as first-line or induction therapy, used in combination with chemotherapy; OR (ii) esophageal squamous cell carcinoma AND BOTH of: used as single agent, used for subsequent therapy; OR (iii) esophageal adenocarcinoma AND BOTH of: HER2 overexpression negative disease, PD-L1 combined positive score ≥ 1
  • ONE of the following: patient has not previously received a checkpoint inhibitor OR no tumor progression while on a checkpoint inhibitor
  • prescribed by or in consultation with an oncologist

Approval duration

1 year