Vyalev (foscarbidopa and foslevodopa subcutaneous injection) — Medica

Initial criteria

• Patient is diagnosed with advanced Parkinson’s disease
• Patient is experiencing 'off' episodes such as muscle stiffness, slow movements, or difficulty starting movements
• Patient has tried an oral carbidopa/levodopa therapy and meets ONE of the following (i or ii): i) Patient had significant intolerance, according to the prescriber; OR ii) Patient had inadequate efficacy, according to the prescriber
• Patient has previously tried or is currently receiving ONE other treatment for 'off' episodes (e.g., entacapone, rasagiline, pramipexole, ropinirole, tolcapone, cabergoline, selegiline, Ongentys [opicapone], or Xadago [safinamide])
• Medication is prescribed by or in consultation with a neurologist

Approval duration

1 year