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Wainua (eplontersen)Medica

polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR)

Initial criteria

  • age ≥ 18 years
  • has a transthyretin (TTR) pathogenic variant confirmed by genetic testing
  • has symptomatic polyneuropathy
  • does not have a history of liver transplantation
  • prescribed by or in consultation with a neurologist, geneticist, or physician who specializes in treatment of amyloidosis
  • not used in combination with other medications indicated for polyneuropathy of hereditary transthyretin-mediated amyloidosis or transthyretin-mediated amyloidosis-cardiomyopathy (e.g., Amvuttra, Attruby, Onpattro, Tegsedi, tafamidis products)

Approval duration

1 year