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ZepboundMedica

Obstructive sleep apnea, moderate to severe, in a patient with obesity

Initial criteria

  • age ≥ 18 years
  • current BMI ≥ 30 kg/m2
  • sleep study showing diagnosis of moderate to severe OSA with apnea-hypopnea index ≥ 15 events/hour
  • does not have central sleep apnea with ≥ 50% central apneas/hypopneas AND does not have Cheyne Stokes respiration
  • used concomitantly with behavioral modification and reduced-calorie diet

Reauthorization criteria

  • age ≥ 18 years
  • baseline BMI ≥ 30 kg/m2
  • has completed ≥ 1 year of Zepbound therapy
  • has lost ≥ 10% of baseline body weight
  • has stability in OSA signs or symptoms (e.g., snoring, daytime sleepiness, fatigue)
  • used concomitantly with behavioral modification and reduced-calorie diet

Approval duration

1 year