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DupixentMedical Mutual

Prurigo Nodularis

Initial criteria

  • Patient is age ≥ 18 years; AND
  • Patient has ≥ 20 nodular lesions on arms, legs, or trunk; AND
  • Pruritus for ≥ 3 months; AND
  • Condition not medication-induced or secondary cause managed; AND
  • Patient did not respond or is not candidate for ≥ 3 months of topical therapy, systemic therapy, and/or phototherapy (two of three required); AND
  • Prescribed by or in consultation with allergist, immunologist, or dermatologist

Reauthorization criteria

  • Patient has received ≥ 6 months Dupixent; AND
  • Patient has clinical response (reduced nodular lesion count, decreased pruritus, reduced lesion size)

Approval duration

6 months initial, 1 year reauth