Efudex 5% cream — Medical Mutual
Actinic keratosis
Preferred products
- fluorouracil 2% solution
 - fluorouracil 5% solution
 - fluorouracil 5% cream
 - imiquimod 5% cream
 
Initial criteria
- If the patient has tried one preferred product, then authorization for a non-preferred product may be given.
 - Step Therapy Exception Criteria: Approve for 1 year if the patient meets ONE of the following (A, B, or C):
 - A. The patient has an atypical diagnosis and/or unique patient characteristics which prevent use of all preferred agents; OR
 - B. The patient has a contraindication to all preferred agents; OR
 - C. The patient is continuing therapy with the requested non-preferred agent after being stable for at least 90 days AND meets ONE of the following:
 - 1. The patient has at least 130 days of prescription claims history on file and claims history supports that the patient has received the requested non-preferred agent for 90 days within a 130-day look-back period AND there is no generic equivalent available for the requested nonpreferred product; OR
 - 2. When 130 days of the patient’s prescription claims history file is unavailable for verification, the prescriber must verify that the patient has been receiving the requested non-preferred agent for 90 days AND that the patient has been receiving the requested non-preferred agent via paid claims AND there is no generic equivalent available for the requested nonpreferred product.
 
Reauthorization criteria
- All approvals for continuation of therapy are provided for 1 year unless noted otherwise.
 
Approval duration
1 year