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ImvexxyMedical Mutual

Moderate to severe dyspareunia resulting from vulvar and vaginal atrophy, a symptom of menopause

Initial criteria

  • Patient is a post-menopausal woman with vulvar and/or vaginal atrophy; AND
  • Patient has had an inadequate response to at least one low-dose vaginal estrogen preparation (e.g. generic estrogen vaginal cream, generic estrogen vaginal insert, Yuvafem, Premarin vaginal cream, Estrace vaginal cream, Estring, Vagifem); AND
  • Patient does not have any contraindications to use of estrogens (e.g. history of breast cancer, estrogen-dependent neoplasia, undiagnosed abnormal genital bleeding, liver disease/impairment, history of or active DVT, PE, stroke, or MI); AND
  • Imvexxy will not be used in combination with other estrogen preparations, Osphena, or Intrarosa

Reauthorization criteria

  • The patient meets all the initial criteria; AND
  • The patient has had an improvement on Imvexxy per the prescribing physician

Approval duration

initial: 3 months; extended: 1 year