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JoenjaMedical Mutual

Activated Phosphoinositide 3-kinase Delta Syndrome (APDS), initial therapy

Initial criteria

  • Patient is ≥ 12 years of age
  • Patient weighs ≥ 45 kg
  • Patient has a genetic phosphoinositide 3-kinase delta (PI3Kδ) mutation with a variant in PIK3CD and/or PIK3R1 genes
  • Patient has at least one clinical finding or manifestation consistent with APDS
  • The medication is prescribed by or in consultation with an immunologist or a physician who treats patients with primary immune deficiencies

Approval duration

6 months