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PraluentMedical Mutual

Primary hyperlipidemia not associated with CVD, HeFH, or HoFH

Initial criteria

  • Patient age ≥ 18 years; AND
  • Patient has one of the following: (a) Coronary artery calcium score ≥ 300 Agatston units; OR (b) Diabetes; AND
  • Patient meets one of: (a) Tried high-intensity statin (atorvastatin ≥ 40 mg daily OR rosuvastatin ≥ 20 mg daily) AND ezetimibe (single or combo) for ≥ 8 weeks AND LDL-C remains ≥ 70 mg/dL; OR (b) Statin intolerance (rhabdomyolysis OR muscle symptoms on separate trials of atorvastatin and rosuvastatin resolving upon discontinuation)

Reauthorization criteria

  • Prescriber attests patient has experienced a response to therapy (e.g., decreased LDL-C, total cholesterol, non-HDL-C, or apolipoprotein B)

Approval duration

1 year