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RozlytrekMedical Mutual

Solid Tumors (NTRK gene fusion-positive)

Initial criteria

  • Patient age ≥ 12 years
  • Tumor has NTRK gene fusion without a known acquired resistance mutation
  • Tumor is metastatic OR surgical resection will likely result in severe morbidity
  • Patient has progressed following treatment OR there are no satisfactory alternative therapies

Reauthorization criteria

  • Patient has not experienced intolerable side effects
  • Patient has had a beneficial response to therapy, per the prescribing physician

Approval duration

1 year