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Symdeko (tezacaftor/ivacaftor and ivacaftor)Medical Mutual

Cystic Fibrosis (CF), continuation of therapy

Initial criteria

  • Patient has been using Symdeko for at least 6 months; AND
  • Patient meets all criteria for new starts

Reauthorization criteria

  • Compared to baseline, patient has experienced clinical benefit in response to therapy such as: i. Increase in weight; OR ii. Improvement in sweat chloride; OR iii. Improvement in predicted FEV1 or other lung function tests; OR iv. Decrease in amount/frequency of pulmonary exacerbations; OR v. Decrease in amount/frequency of pulmonary infections; OR vi. Decrease in hospitalizations

Approval duration

1 year