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TarpeyoMedical Mutual

Primary Immunoglobulin A Nephropathy (IgAN), initial therapy

Initial criteria

  • Patient is ≥ 18 years of age
  • The diagnosis has been confirmed by biopsy
  • Patient is at high risk of disease progression, defined by meeting the following criteria (a and b):
  • a. Patient meets ONE of the following: i. Proteinuria > 0.5 g/day; OR ii. Urine protein-to-creatinine ratio ≥ 0.8g/g
  • b. Patient has been receiving the maximum or maximally tolerated dose of ONE of the following for ≥ 90 days: i. Angiotensin converting enzyme inhibitor (ACEi); or ii. Angiotensin receptor blocker (ARB)
  • According to the prescriber, the patient has received ≥ 90 days of optimized supportive care, including blood pressure management, lifestyle modification, and cardiovascular risk modification
  • Patient has an estimated glomerular filtration rate (eGFR) ≥ 30 mL/min/1.73 m2
  • Patient has not previously been treated with Tarpeyo
  • The medication is prescribed by or in consultation with a nephrologist

Approval duration

10 months