tolvaptan (generic of Jynarque) — Medical Mutual
autosomal dominant polycystic kidney disease (ADPKD) - at risk of rapidly progressing disease
Initial criteria
- Medication requested is being used to slow kidney function decline
 - Patient age ≥ 18 years
 - Liver function laboratory values (ALT, AST, bilirubin) have been reviewed and are appropriate before initiation
 - Requested drug is prescribed by or under consultation with a nephrologist
 
Reauthorization criteria
- Medication requested is being used to slow kidney function decline
 - Requested drug is prescribed by or under consultation with a nephrologist
 - Patient’s kidney function (total kidney volume, albuminuria, onset or progression of hypertension, eGFR, etc.) decline has slowed and/or kidney pain has improved since treatment
 - Provider is monitoring liver function monthly for the first 18 months of treatment, then every 3 months
 
Approval duration
initial 90 days; reauth 1 year