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apomorphine hydrochloride subcutaneous injection — Point32Health

Parkinson’s Disease with OFF episodes despite maximizing carbidopa/levodopa dose

Initial criteria

  • Diagnosis of Parkinson’s Disease
  • Patient is experiencing OFF episodes with carbidopa/levodopa therapy despite maximizing dose
  • Medication is prescribed by, or in consultation with, a neurologist
  • Patient is currently taking, or has had trial and failure, inadequate response, intolerance, or contraindication to TWO of the following (must be from two different classes): Dopamine agonist (e.g., pramipexole, ropinirole), Catechol-o-methyl transferase (COMT) inhibitor (e.g., entacapone), Monoamine oxidase (MAO) B inhibitor (e.g., rasagiline, selegiline)
  • Medication will be used in combination with carbidopa/levodopa