Releuko — Point32Health
Glycogen Storage Disease Type 1 with documented low neutrophil count
Preferred products
- Zarxio
Initial criteria
- For prophylaxis of chemotherapy-induced neutropenia: Documentation of solid tumor or non-myeloid malignancy in a patient receiving myelosuppressive chemotherapy AND one of the following:
- • Chemotherapy regimen associated with a high risk (>20%) of febrile neutropenia based on NCCN guidelines
- • Chemotherapy regimen with intermediate risk (10–20%) of febrile neutropenia AND patient has ≥1 risk factor: age ≥65 years, active infection/open wound/recent surgery, advanced disease (stage 2 or higher or bone marrow involvement), prior chemotherapy or radiation therapy, pre-existing neutropenia, poor ECOG performance status (2–5) or poor nutritional status, comorbidities (cardiovascular, renal [CrCl <50], or hepatic [bilirubin >2.0], HIV), difficulty recognizing or managing fever, or chronic immunosuppression post-transplant
- • Patient receiving dose-dense myelosuppressive chemotherapy
- • Patient has experienced neutropenic complication (febrile neutropenia or dose-limiting neutropenia) from prior cycle of same chemotherapy
- OR diagnosis of acute myeloid leukemia scheduled for induction or consolidation chemotherapy
- OR diagnosis of non-myeloid malignancy receiving myeloablative chemotherapy followed by bone marrow transplantation
- Other requested use is for one of the specified conditions in indications list above
- In addition, documented previous failure, contraindication, or clinical inappropriateness with Zarxio
Approval duration
6 months