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Vowst (fecal microbiota spores, live-brpk)Point32Health

Prevention of recurrence of Clostridioides difficile infection (CDI) following antibacterial treatment for recurrent CDI

Initial criteria

  • Documentation the Member has had three or more episodes of Clostridioides difficile infection in the previous twelve months
  • AND Member age ≥ 18 years
  • AND Documentation that Vowst is prescribed by or in consultation with a specialist (e.g., infectious disease, gastroenterologist)
  • AND Patient had a recent episode of recurrent C. difficile infection with documentation of all the following:
  • — Patient had no more than 2 unformed stools for 2 consecutive days
  • — C. difficile infection has been treated with an antibiotic within the past 5 days of requesting the PA for Vowst
  • — Most recent treatment was with one of the following antibiotics: vancomycin or fidaxomicin

Approval duration

1 month